Penicillin and the present-day concept of its clinical applicability.
Read Online

Penicillin and the present-day concept of its clinical applicability.

  • 324 Want to read
  • ·
  • 58 Currently reading

Published by Pharmaceutical division, Commercial solvents corporation in New York, N.Y .
Written in English


  • Penicillin

Book details:

Edition Notes

Bibliographical foot-notes.

LC ClassificationsRS165.P38 C6
The Physical Object
Pagination71 p.
Number of Pages71
ID Numbers
Open LibraryOL28979M
LC Control Numbersg 44000201

Download Penicillin and the present-day concept of its clinical applicability.


its large-scale production transformed the pharmaceutical industry, and its clinical use changed forever the therapy for infectious diseases. The success of penicillin production in Great Britain and the United States overshadowed the serendipity of its production . After just over 75 years of clinical use, it is clear that penicillin’s initial impact was immediate and profound. Its detection completely changed the process of drug discovery, its large-scale production transformed the pharmaceutical industry, and its clinical use .   The present book and an as yet unpublished fourth volume are intended to consider the clinical aspects, respectively, of penicillin and other antibiotics. The motives in devoting an entire volume to a discussion of penicillin are quickly established by Dr. Florey in the preface of this book. The use of broad-spectrum antibiotics in patients labeled “penicillin-allergic” is associated with higher healthcare costs, increased risk for antibiotic resistance, and suboptimal antibiotic therapy.1 5. Correctly identifying those who are not truly penicillin-allergic can decrease unnecessary use of broad-spectrum antibiotics.1File Size: KB.

  The discovery of penicillin, one of the world's first antibiotics, marks a true turning point in human history -- when doctors finally had a tool that could completely cure their patients of Author: Dr. Howard Markel. THE issue of the British Medical Journal dated April 15 includes eight papers which record the results of work done at one of the four main centres established in March by the Penicillin. penicillin G correlates inversely with age and clearance of creatinine and ranges from hours in infants 0 to 6 days of age to hours in infants 14 days of age or older. Nonrenal clearance includes hepatic metabolism and, to a lesser extent, biliary excretion. Penicillin, one of the first and still one of the most widely used antibiotic agents, derived from the Penicillium mold. In Scottish bacteriologist Alexander Fleming first observed that colonies of the bacterium Staphylococcus aureus failed to grow in those areas of a culture that had been accidentally contaminated by the green mold Penicillium notatum.

  Clinical use of penicillin antibiotics. April 8, Gaurab Karki Pharmaceutical Microbiology 0. Clinical use of penicillin antibiotics 1. Penicillin G: Penicillin G is the drug of choice in infection caused by Pneumococci, Streptococci, Meningococci, Gonococci and Staphylococci (Non β-lactamase producing Staphylococci). An exciting lime Finally, I would like to say that the penicillin discovery does not end with the TIPS - inauKural issue, 11 discovery of ils curative properties in the s. I cJn say thai since (he firsi day I loucned the subsiance unlil the present day, work on penicillin has brought a con- tinuous by:   Penicillin V is an antibiotic in the penicillin group of drugs. It fights bacteria in your body. Penicillin V is used to treat many different types of infections caused by bacteria, such as ear infections,. Penicillin V may also be used for other purposes not listed . The discovery of penicillin and the initial recognition of its therapeutic potential occurred in the United Kingdom, but, due to World War II, the United States played the major role in developing large-scale production of the drug, thus making a life-saving substance .